Parvovirus B19 infection mimicking systemic lupus erythematosus, successfully treated with intravenous immune globulin

Parvovirus infection mimicking systemic lupus erythematosus.

There are striking similarities between human parvovirus B19 (HPV-B19) infection and systemic lupus erythematosus (SLE): both may present with malar rash, fever, arthropathy, myalgia, cytopenia, hypocomplementemia, anti-DNA, and antinuclear antibodies (ANA). Therefore, it is difficult at times to differentiate HPV-B19 infection from SLE presentation or exacerbation. We report 4 cases of HPV-B19...

Human parvovirus B19 infection in patients with systemic lupus erythematosus.

OBJECTIVE The clinical significance of the presence of B19 DNA in patients with SLE was studied. METHODS Sera from 72 patients with systemic lupus erythematosus (SLE), 23 patients with rheumatoid arthritis (RA), 18 patients with Sjögren's syndrome (SS), eight patients with Raynaud's phenomenon (RP), five patients with primary biliary cirrhosis (PBC), five patients with polymyositis (PM), four...

Pediatric systemic lupus erythematosus and human parvovirus B19 infection

Results 3 girls aged from 8 years to 15 years 8 months have been included. PB19 infection was present at diagnosis in all patients. Maternal history of autoimmune diseases was noted in a consanguineous family. Clinical manifestations at diagnosis were fever(3), arthritis/arthralgia (3), skin rash (1), grade IV glomerulonephritis (1), interstitial pneumonia (1), cerebral vasculitis (1), pericard...

Parvovirus B19 viremia in children with systemic lupus erythematosus

INTRODUCTION Human parvovirus B19 (PB19) is a single-stranded DNA virus that was first discovered in 1975 by Yvonne Cossart and her colleagues. It has been associated with a variety of clinical manifestations, including rash, thrombocytopenia, leukopenia, fetal wastage, hypocomplementemia, autoimmune hemolytic anemia, arthritis and vasculitis. It is the causative agent of erythema infectiosum (...

High-dose intravenous gamma-globulin in systemic lupus erythematosus.